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Tirzepatide demonstrated a lower risk of the secondary composite endpoint in heart failure hospitalization, urgent heart failure visit or all-cause mortality compared to dulaglutide HR 0.75 (95% CI 0.65 to 0.86)

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Taking a GLP-1 injection slightly early is generally not harmful, but doses given too close together may increase the risk of side effects such as nausea, vomiting, or abdominal discomfort

More than 1 in 8 patients became completely free from knee pain by the end of the study